Transcriptional and Post-Transcriptional Regulation of Proangiogenic Factors by the Unfolded Protein Response
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چکیده
منابع مشابه
Transcriptional and Post-Transcriptional Regulation of Proangiogenic Factors by the Unfolded Protein Response
BACKGROUND Inadequate extracellular conditions can adversely affect the environment of the ER and impinge on the maturation of nascent proteins. The resultant accumulation of unfolded proteins activates a signal transduction pathway, known as the unfolded protein response, which serves primarily to protect the cell during stress and helps restore homeostasis to the ER. PRINCIPAL FINDINGS Micr...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0012521